Peptide vaccines based on tumor antigens face the challenges of rapid clearance of peptides, low immunogenicity, and immune suppressive tumor microenvironment.However, the traditional solution mainly uses exogenous substances as adjuvants or carriers to enhance innate immune responses, but excessive inflammation can damage adaptive immunity.In the
Ranking search results is essential for information retrieval and Web search.Search engines need to not only return highly relevant results, but also be fast to satisfy users.As a result, not all available features can be used for ranking, and in fact only a small percentage Mousepad of these features can be used.Thus, it is crucial to have a featu
Onychomycosis is a common fungal infection of the nail, caused by dermatophytes, non-dermatophytes, and yeasts.Predisposing factors include older age, trauma, diabetes, immunosuppression, and previous history of nail psoriasis or tinea pedis.Though many biological risk factors have been well characterized, the role of the environment has been less
Abstract Background Recent evidence suggests that several Vests human cancers are capable of uncoupling of mitochondrial ATP generation in the presence of intact tricarboxylic acid (TCA) enzymes.The goal of the current study was to test the hypothesis that ketone bodies can inhibit cell growth in aggressive cancers and that expression of uncoupling